Date de signature : | 23/09/2024 | Statut du texte : | En vigueur |
Date de publication : | 24/09/2024 | Emetteur : | |
Consolidée le : | Source : | JOUE Série L du 24 septembre 2024 | |
Date d'entrée en vigueur : | 14/10/2024 |
Propriétés physicochimiques de base |
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Effet mesuré |
Méthode d’essai |
Chapitre correspondant, contenant la description complète de la méthode d’essai, dans la partie A de la présente annexe (les références entre parenthèses indiquent que la description complète de la méthode d’essai a été supprimée de la partie A; cellule vide: aucune méthode d’essai correspondante ne figure dans la partie A de la présente annexe) |
Point de fusion/point de congélation |
OECD Test Guideline 102: Melting Point/Melting Range (1995) |
A.1 |
ASTM D4359-90: Standard Test Method for Determining whether a Material Is a Liquid or a Solid |
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Test for determining fluidity according to section 2.3.4 of Annex A of the Agreement concerning the International Carriage of Dangerous Goods by Road (ADR) |
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Point d’ébullition |
OECD Test Guideline 103: Boiling point (1995) |
A.2 |
Test methods according to Table 2.6.4 of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Inflammabilité |
EN 15188:2020 – Determination of the spontaneous ignition behaviour of dust accumulations |
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Limites inférieure et supérieure d’explosivité |
Test methods according to section 2.2.4.1. of Annex I, Part 2 of Regulation (EC) N°1272/2008 (ISO 10156 and EN 1839) |
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Point d’éclair |
Test methods according to table 2.6.3 of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Température d’inflammation spontanée (liquides, gaz) |
ISO/IEC 80079-20-1:2017 – Explosive atmospheres - Part 20-1: Material characteristics for gas and vapour classification - Test methods and data |
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Température de décomposition |
Calorimetric test methods according to section 20.3.3.3 of Part II of the UN Manual of Tests and Criteria |
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Test Series H, part II, section 28, of the UN Manual of Tests and Criteria for the self-accelerating decomposition temperature (SADT) (with reference to a specific package) |
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pH |
OECD Test Guideline 122: Determination of pH, Acidity and Alkalinity (2013) |
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Viscosité cinématique |
OECD Test Guideline 114: Viscosity of Liquids (2012) |
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Solubilité dans l’eau |
OECD Test Guideline 105: Water Solubility (1995) |
A.6 |
Coefficient de partage n-octanol/eau |
OECD Test Guideline 107: Partition Coefficient (n-octanol/water): Shake-Flask Method (1995) |
(A.8) |
OECD Test Guideline 123: Partition Coefficient (1-Octanol/Water): Slow-Stirring Method (2022) |
A.23 |
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OECD Test Guideline 117: Partition Coefficient (n-octanol/water): HPLC Method (2022) |
A.24 |
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Pression de vapeur |
OECD Test Guideline 104: Vapour Pressure (2006) |
(A.4) |
Densité/densité relative |
OECD Test Guideline 109: Density of Liquids and Solids (2012) |
(A.3) |
DIN 66137-2 - Determination of solid state density - Part 2: Gas pycnometry |
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ISO 12154 - Determination of density by volumetric displacement - Skeleton density by gas pycnometry |
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Caractéristiques des particules |
EU test method A.22. Length Weighted Geometric Mean Diameter of Fibres |
A.22. |
ISO 21501 - Determination of Particle Size Distribution - Single Particle Light Interaction Methods |
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OECD Test Guideline 124: Determination of the Volume Specific Surface Area of Manufactured Nanomaterials (2022) |
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OECD Test Guideline 125: Particle Size and Particle Size Distribution of Nanomaterials (2023) |
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ISO/TR 14187:2020 - Surface chemical analysis -Characterization of nanostructured materials |
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Pouvoir de resuspension (pour les nanoformes d’une substance) |
EN 17199-1:2019 – Workplace exposure - Measurement of dustiness of bulk materials that contain or release respirable NOAA and other respirable particles |
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EN 15051-1: Workplace exposure - Measurement of the dustiness of bulk materials - Part 1: Requirements and choice of test methods |
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EN 15051-2: Workplace exposure - Measurement of the dustiness of bulk materials - Part 2: Rotating drum method |
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EN 15051-3: Workplace exposure - Measurement of the dustiness of bulk materials - Part 3: Continuous drop method |
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Tension superficielle |
OECD Test Guideline 115: Surface Tension of Aqueous Solutions (1995) |
A.5 |
Constante de dissociation |
OECD Test Guideline 112: Dissociation Constants in Water. (1981) |
A.25 |
Hydrophobicité |
OECD Test Guideline 126: Determination of the Hydrophobicity Index of Manufactured Nanomaterials Through an Affinity Measurement (2023) |
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Propriétés physicochimiques dangereuses |
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Explosibles |
Test methods for explosives according to section 2.1.2.1. and 2.1.2.3. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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EU Test method A.14 Explosive Properties |
A.14 |
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Gaz inflammables |
Test method for the fundamental burning velocity according to section 2.2.4.1. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Test method for pyrophoric gases according to section 2.2.4.2. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Test method for the chemical instability according to section 2.2.4.4. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Gaz comburants |
Test method for oxidising gases according to section 2.4.4. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Liquides inflammables |
Test method for the sustained combustibility according to section 2.6.4.5. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Test methods for determining the flash point of flammable liquids according to section 2.6.4.4. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Matières solides inflammables |
Test method for flammable solids according to section 2.7.2.3. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Substances autoréactives |
Test method for self-reactive substances according to section 2.8.4.1. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Liquides pyrophoriques |
Test method for pyrophoric liquids according to section 2.9.2.1. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Matières solides pyrophoriques |
Test method for pyrophoric solids according to section 2.10.2.1. of Annex I, Part 2 of Regulation (EC) N°1272/2008, |
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Substances auto-échauffantes |
Test method for self-heating substances according to section 2.11.2.2 of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Substances qui, au contact de l’eau, dégagent des gaz inflammables |
Test method for substances which in contact with water emit flammable gases according to section 2.12.2.1. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Liquides comburants |
Test method for oxidising liquids according to section 2.13.2.1. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Matières solides comburantes |
Test method for oxidising solids according to section 2.14.2.1. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Peroxydes organiques |
Test methods according to section 2.15.4.1 of Annex I, Part 2 of Regulation (EC) No 1272/2008 |
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Substances ou mélanges corrosifs pour les métaux |
Test method for substances corrosive to metals according to section 2.16.2.1. of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Explosibles désensibilisés |
Test methods according to section 2.17.2.1 (b) and (c) and according to section 2.17.2.2 of Annex I, Part 2 of Regulation (EC) N°1272/2008 |
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Propriétés des polymères |
OECD Test Guideline 118: Determination of the Number-Average Molecular Weight and the Molecular Weight Distribution of Polymers using Gel Permeation Chromatography (1996) |
A.18 |
OECD Test Guideline 119: Determination of the Low Molecular Weight Content of a Polymer Using Gel Permeation Chromatography (1996) |
A.19 |
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OECD Test Guideline 120: Solution/Extraction Behaviour of Polymers in Water (2000) |
(A.20.)» |
«Lésions oculaires graves/irritation oculaire |
In vitro: |
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OECD Test Guideline 437: Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage (2023) |
(B.47.) |
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OECD Test Guideline 438: Isolated Chicken Eye Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage (2023) |
(B.48) |
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OECD Test Guideline 460: Fluorescein Leakage Test Method for Identifying Ocular Corrosives and Severe Irritants (2023) |
(B.61) |
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OECD Test Guideline 491: Short Time Exposure In Vitro Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage (2023) |
(B.68.) |
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OECD Test Guideline 492: Reconstructed human Cornea-like Epithelium (RhCE) Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage (2023) |
(B.69.) |
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OECD Test Guideline 492B: Reconstructed Human Cornea-like Epithelium (RHCE) Test Method for Eye Hazard Identification (2022) |
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OECD Test Guideline 494: Vitrigel-Eye Irritancy Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage (2021) |
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OECD Test Guideline 496: In vitro Macromolecular Test Method for Identifying Chemicals Inducing Serious Eye Damage and Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage (2023) |
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OECD Test Guideline 467: Defined Approaches for Serious Eye Damage and Eye Irritation (2022) |
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In vivo: |
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OECD Test Guideline 405: Acute Eye Irritation/Corrosion (2023) |
(B.5.)» |
«In vitro: |
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OECD Test Guideline 442C: In Chemico Skin Sensitisation Assays addressing the Adverse Outcome Pathway key event on covalent binding to proteins (2023) |
(B.59) |
OECD Test Guideline 442D: In Vitro Skin Sensitisation Assays Addressing the AOP Key Event on Keratinocyte Activation (2022) |
(B.60.) |
OECD Test Guideline 442E: In Vitro Skin Sensitisation: In Vitro Skin Sensitisation Assays Addressing the Key Event on Activation of Dendritic Cells on the Adverse Outcome Pathway for Skin Sensitisation (2023) |
(B.71.)» |
OECD Test Guideline 497: Defined Approaches on Skin Sensitisation (2023); |
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«OECD Test Guideline 487. In vitro Mammalian Cell Micronucleus Test (2016) |
B.49» |
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«OECD Test Guideline 487. In vitro Mammalian Cell Micronucleus Test (2023) |
(B.49.)» |
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«OECD Test Guideline 456: H295R Steroidogenesis Assay (2022) |
B.57.» |
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OECD Test Guideline 458: Stably Transfected Human Androgen Receptor Transcriptional Activation Assay for Detection of Androgenic Agonist and Antagonist Activity of Chemicals (2020) |
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«OECD Test Guideline 456: H295R Steroidogenesis Assay (2023) |
(B.57.)» |
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OECD Test Guideline 458: Stably Transfected Human Androgen Receptor Transcriptional Activation Assay for Detection of Androgenic Agonist and Antagonist Activity of Chemicals (2023); |
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«OECD Test Guideline 498: In Vitro Phototoxicity Test Method Using the Reconstructed Human Epidermis (RhE) (2021)» |
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«OECD Test Guideline 498: In Vitro Phototoxicity Reconstructed Human Epidermis Phototoxicity test method (2023)» |
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«Immunotoxicité |
OECD Test Guideline 444A: In vitro immunotoxicity IL-2 Luc assay (2023)» |
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«OECD Test Guideline 316: Phototransformation of Chemicals in Water – Direct Photolysis (2008)» |
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«OECD Test Guideline 316: Phototransformation of Chemicals in Water – Direct Photolysis (2023)» |
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«OECD Test Guideline 218: Sediment-Water Chironomid Toxicity Using Spiked Sediment (2004) |
C.27 |
OECD Test Guideline 219: Sediment-Water Chironomid Toxicity Using Spiked Water (2004) |
C.28» |
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«OECD Test Guideline 218: Sediment-Water Chironomid Toxicity Test Using Spiked Sediment (2023) |
(C.27.) |
OECD Test Guideline 219: Sediment-Water Chironomid Toxicity Test Using Spiked Water (2023) |
(C.28.)» |
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«OECD Test Guideline 240: Medaka Extended OneGeneration Reproduction Test (MEOGRT) (2015) |
C.52» |
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«OECD Test Guideline 240: Medaka Extended One Generation Reproduction Test (MEOGRT) (2023) |
(C.52.)» |